![]() If you share the toilet with other people, wipe the toilet seat after using it.For 7 days, flush the toilet twice after using it.For 7 days, wipe yourself very carefully after having your bowels open (some hospitals suggest that you use gloves).Wash your hands thoroughly every time you use the toilet.For the first few days sit down on the toilet when passing urine, instead of standing up or using a urinal.The team looking after you might ask you to take the following precautions. ![]() The total amount is extremely small and gets lower each day. After treatmentĪfter the treatment, some radiation may be present in your wee (urine) and poo (stool) for up to 7 days. You have the treatment as an outpatient and can go home afterwards. You usually have it up to 6 times. You might have a blood test in between injections to make sure it is safe for you to have your next one. You normally have the injection every 4 weeks. Usually this is through a thin short tube (cannula) which is put into a vein in your arm or hand each time you have treatment. You have radium 223 as an injection into a vein. Your doctor will let you know about this. You might have to stop taking calcium supplements before treatment. You might also have a bone scan a week or so before. You have a blood test before treatment to make sure you're well enough to have it. So this treatment causes few side effects. This means that the cancer cells receive a high dose of radiation which can destroy them. And healthy cells receive only a low dose or no radiation. The cancer cells in the bone take up radium 223 and it then releases radiation which travels a very short distance. This is because it is similar to calcium, which is also absorbed by bone cells. are not having treatment with abiraterone.have cancer that has spread to bones but not other organs.have either had or aren't suitable for docetaxel (chemotherapy drug).had hormone treatment that is no longer working.Radium 223 is for people with prostate cancer who: You might need to travel to a different hospital for the treatment because it isn’t available in every hospital. ![]() This reduces symptoms, such as pain, and helps you feel more comfortable. Radium 223 can shrink areas of cancer cells that have spread to the bone. You have this treatment in the nuclear medicine department. It's brand name is Xofigo (pronounced zoh-fee-go). Radium 223 is a mildly radioactive form of the metal radium. This is metastatic or advanced prostate cancer. You might have it for cancer that began in the prostate and has spread to the bones. Internal radiotherapy means giving radiotherapy to the cancer from inside the body. Radium 223 is a type of internal radiotherapy treatment. The study has now been terminated, even though more than 1,000 subjects with measured radium burdens are still alive.Radium 223 (Xofigo) for metastatic prostate cancer The Argonne study is the largest every undertaken of the effects on humans of an internally deposited radioelement, in which the insult has been quantitated by actual measurements of the retained radioisotope. Nevertheless, great gaps remain in the knowledge of radium toxicity. As a consequence of the efforts made to locate, measure, and follow exposed individuals, a great deal of information about the effects of radium is available. Some of this group have been located and followed until death in these cases the cause of death is known without a body content measurement. Many more individuals acquired radium internally but were never measured. Some 2,400 subjects have had their body contents of radium measured, and a majority of them have been followed for most of their adult lives, to understand and quantify the effects of radium. ![]() The effects of internally deposited radium in humans have been studied in this country for more than 75 years. The extensive references included will allow the interested reader to find additional information. Further, because the Argonne studies were not the only such efforts, brief overviews of the other radium programs are included. It soon became evident, however, that to document the widespread use of radium, a brief review of the application of radium in medicine and in the US dial painting industry is required. This document was originally conceived as a description of the radium studies that took place at Argonne National Laboratory.
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